NICE technology appraisal

for Hybrid Closed Loop systems

NICE now recommends Hybrid Closed Loop (HCL) systems for selected people with type 1 diabetes1

Man wearing FreeStyle Libre 3 Plus sensor and Omnipod system
Man wearing FreeStyle Libre 3 Plus sensor and Omnipod system
Man wearing FreeStyle Libre 3 Plus sensor and Omnipod system

The new NICE technology appraisal recommendation means more type 1 patients qualify for a Hybrid Closed Loop (HCL) compatible CGM system

NICE guidelines for HCL

NICE recommends HCL1 as an option for managing blood glucose levels in type 1 diabetes in:

  • Adults with HbA1c ≥7.5% (58 mmol/mol), or who have disabling hypoglycaemic episodes despite continuous subcutaneous insulin (CSII), real-time continuous glucose monitoring (rtCGM) or intermittently scanned CGM (isCGM)

  • Children and young people

  • Those who are pregnant or are planning pregnancy

image of a healthcare professional and a patient

Benefits of HCL systems1,2

decrease in A1c icon decrease in A1c icon

Improved HbA1c

glucose graph icon glucose graph icon

Increased Time in Range

reduced hypoglycaemia icon reduced hypoglycaemia icon

Reduced hypoglycaemia

stress icon stress icon

Reduced diabetes distress

swim icon swim icon

Improved quality of life

 FreeStyle Libre systems* & partnerships

Accurate, minute-to-minute glucose data combined with automated insulin delivery

Connected insulin pumps can prevent low and high glucose levels by automatically adjusting insulin delivery based on Libre 2 Plus, or Libre 3 Plus sensor readings.

FreeStyle Libre 2 and Libre 3 Plus sensor

Omnipod® 5 Automated Insulin Delivery System

Authorised to work with the Libre 3 Plus and Libre 2 Plus sensors

Our 15-day sensors and the Omnipod 5 Automated Insulin Delivery system (AID) create one easy^, integrated experience for your patients.

Note that users should start their Libre 3 Plus or 2 Plus sensor with the Omnipod 5 System.

Libre 3 plus and Libre 2 plus integration with Omnipod 5 system Pod shown without the necessary adhesive.
FreeStyle Libre 3 Plus sensor lasts 15 days

Tandem Automated Insulin Delivery System

Authorised to work with the Libre 3 Plus sensor

The Libre 3 Plus sensor and Tandem Diabetes Care AID system create one easy^, integrated experience.

Note that users should start their Libre 3 Plus sensor with the Tandem t:slim mobile app.

Libre 3 Plus sensor and the Tandem AID system Not actual patient data. For illustrative purposes only.
FreeStyle Libre 3 Plus sensor lasts 15 days

Authorised to work with the Libre 3 Plus sensor

Minute-to-minute glucose readings combined with the myLoop automated insulin delivery system for easier diabetes management for your patients.3,^

Note that users should start their Libre 3 Plus sensor with the CamAPS FX app.

Libre 3 Plus sensor connected to the CamAPS FX app and YpsoPump via Bluetooth, with the app showing a glucose reading of 5.4 mmolL. Libre 3 Plus sensor connected to the CamAPS FX app and YpsoPump via Bluetooth, with the app showing a glucose reading of 5.4 mmolL. Libre 3 Plus sensor connected to the CamAPS FX app and YpsoPump via Bluetooth, with the app showing a glucose reading of 5.4 mmolL.

References & Disclaimers

Images are for illustrative purposes only. Not real patients, healthcare professionals, or data.

Omnipod is a registered trademark of Insulet Corporation and used with permission. Other trademarks are the property of their respective owners. The FreeStyle Libre 3 Plus and Libre 2 Plus sensors are authorised to work with the Omnipod 5 Automated Insulin Delivery System.

myLoop and YpsoPump are registered trademarks of mylife Diabetes Care AG or of its affiliates. CamAPS is a registered trademark of CamDiab Ltd.

Tandem Diabetes Care, Tandem logos, Control-IQ+, t:slim, t:slim X2, Tandem t:slim Mobile App and Tandem Source are either registered trademarks or trademarks of Tandem Diabetes Care, Inc. in the United States and/or other countries.

* FreeStyle Libre system refers to the FreeStyle Libre 2 and FreeStyle Libre 3 systems.

1. NICE technology appraisal guidance TA943 (2023). Available at https://www.nice.org.uk/guidance/ta943. Accessed October 2026.

2. Crabtree TSJ, Griffin TP, Yap YW, Narendran P, Gallen G, Furlong N, Cranston I, Chakera A, Philbey C, Karamat MA, Saraf S, Kamaruddin S, Gurnell E, Chapman A, Hussain S, Elliott J, Leelarathna L, Ryder REJ, Hammond P, Lumb A, Choudhary P, Wilmot EG; ABCD Closed-Loop Audit Contributors. Hybrid Closed-Loop Therapy in Adults With Type 1 Diabetes and Above-Target HbA1c: A Real-world Observational Study. Diabetes Care. 2023 Oct 1;46(10):1831-1838. doi: 10.2337/dc23-0635. PMID: 37566697; PMCID: PMC10516256.

3. The FreeStyle Libre 3 Plus sensor is authorised for use with the myLoop automated insulin delivery (AID) system, including the CamAPS® FX app and YpsoPump insulin pump. For use of the FreeStyle Libre 3 Plus sensor with the myLoop, refer to the labeling provided with the CamAPS® FX app.

^ Based on product features including up to 15-day wear period, automatic readings every minute, accuracy data, and single-app setup with AID systems.

ADC-2646133 v7.0

Loading...