Time in Range

An important metric that goes beyond HbA1c

Time in Range is a metric that complements HbA1c and provides actionable information for you and your patients. It helps you quickly assess patients’ glucose, contextualise their HbA1c and increase their Time in Range.

What is Time in Range?

Time in Range is the percentage of time per day a person spends within target glucose range. The FreeStyle Libre systems automatically calculate the percentage of time your patient spends in, above, or below target range.

The International Consensus sets clear targets for Time in Range1.

Recommended Time in Range for most T1D, T2D, non-pregnant, not older, or at risk adults regardless of insulin therapy:

Why is Time in Range Important?

  • Every 10% increase in Time in Range can lower HbA1c by 0.8% in type 1 and type 2 patients2

  • Every 5% (~1 hour per day) increase in Time In Range has positive impact on your patients’ glucose control1

  • Spending more Time in Range can reduce long-term eye and kidney health complications3

  • Easily visualise Time in Range and set clear targets for your patients with the FreeStyle Libre Portfolio

Improved %TIR is associated with reduced risk of long term complications of diabetes

Increased %TIR is correlated with reduced risk of diabetes related heart4, kidney3 and eye3 disease, as well as better peripheral nerve function5

HbA1c has limitations

HbA1c reflects average glucose over the last 2–3 months; it does not show glycaemic excursions of hyper- and hypoglycaemia.1

An increase in Time in Range results in a decrease in HbA1c.

Estimate of HbA1c for a given Time in Range level based on T1D and T2D studies2:

Time in Range & The FreeStyle Libre Systems

The FreeStyle Libre systems will automatically calculate the percentage of time your patients spend in, above or below target range. This will help identify where your patient needs more support in managing their overall diabetes health.

This Time in Range report shows a person who spent 75% of their day in target glucose range:

The FreeStyle Libre systems help increase %TIR

An independent study published in the New England Journal of Medicine shows that FreeStyle Libre 2 users increased their Time in Range by over 2 hours per day.6,◊◊

  • 156 people with T1D ≥16 years with HbA1c ≥7.5% paticipated in a randomised, controlled study6

  • FreeStyle Libre 2 users spent 2.2 hours more time in range per day at 6 months of use vs those using self-monitored blood glucose6

Time in range chart

Time in Range & LibreView

Easily visualise Time in Range for your patients with LibreView

LibreView is a secure7, cloud-based diabetes management system. It provides both healthcare professionals and patients with access to a consistent set of clear, intuitive reports that make it easier and faster to discover patterns and trends.

With the AGP report on LibreView you can:

  • See Time in Target guidelines and an overview of patient glucose data
  • Quickly assess your patient’s Time in Range
  • Identify trends and patterns at a glance
  • Identify specific times of deviation with the Daily Glucose Profiles

Additional Resources

Educational Modules

Learn more about Time in Range and the FreeStyle Libre Portfolio through our Healthcare Professional education modules.

Webinars

We offer various on-demand webinars for Healthcare Professionals including Understanding Time in Range.

 

 

 

CME Modules

Take part in our three-part CME accredited webcast programme exploring the growing role of Time In Range as a critical metric of glycemic control in diabetes management.

 

 

Training Resources

Explore our training resources to help you to help your patients understand Time in Range better.

 

References & Disclaimers

Images are for illustrative purposes only. Not real patient or data.

◊ FreeStyle Libre systems refers to the FreeStyle Libre 2 and FreeStyle Libre 3 systems

◊◊ The data from this study was collected using the FreeStyle Libre 2 system. FreeStyle Libre 3 system has the same features as the FreeStyle Libre 2 system, therefore the study data is applicable to both products. Diabetes Care. (2019);42(3):400-405.

1. Battelino T, Danne T, Bergenstal RM, et al. Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range. Diabetes Care. (2019);42(8):1593-1603  

2. Vigersky RA, McMahon C. The relationship of hemoglobin A1c to time-in-range in patients with diabetes. Diabetes Technol Ther. (2019);21(2):81-85    

3. Beck RW et al. Diabetes Care (2019);42(3):400-405.

4. Lu J, et al. Diabetes Technol Ther. 2020 Feb;22:72-78.

5. Li F, et al. Diabetes Res Clin Pract. 2020 Aug;166:108289. doi: 10.1016/j.diabres.2020.108289

6. Leelarathna, L. N Engl J Med. (2022): DOI: 10.1056/NEJMoa2205650.

7. LibreView is ISO27001/27018/27701 certified and HITRUST CSF Certified.

₼ The LibreView website is only compatible with certain operating systems and browsers. Please check www.LibreView.com for additional information.

 

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