Time in Range

An important metric that goes beyond HbA1c

Time in Range is a metric that complements HbA1c and provides actionable information for you and your patients. It helps you quickly assess patients’ glucose, contextualise their HbA1c and increase their Time in Range.

What is Time in Range?

Time in Range is the percentage of time per day a person spends within target glucose range. The FreeStyle Libre 2 system automatically calculates the percentage of time your patient spends in, above, or below target range.

The International Consensus sets clear targets for Time in Range.1,^

Why is Time in Range Important?

  • Every 10% increase in Time In Range = ~0.8% decrease in A1c in type 1 and type 2 patients2

  • Every 5% (1~ hour per day) increase in Time in Range is associated with clinically significant benefits1

  • Increased risk of microvascular complications is associated with decreased Time In Range3

  • Easily visualise Time in Range and set clear targets for your patients with the FreeStyle Libre 2 system

Improved %TIR is associated with reduced risk of long-term complications of diabetes

Increased %TIR is correlated with reduced risk of diabetes related heart4, kidney3 and eye3,5 disease, as well as better peripheral nerve function.6

An increase in Time in Range results in a decrease in HbA1c.2

Estimate of HbA1c for a given Time in Range level based on T1D and T2D studies2:

HbA1c has limitations

HbA1c reflects average glucose over the last 2–3 months; it does not show glycaemic excursions of hyper- and hypoglycaemia.1

Time in Range & The FreeStyle Libre 2 System

The FreeStyle Libre 2 system will automatically calculate the percentage of time your patients spend in, above or below target range. This will help identify where your patient needs more support in managing their overall diabetes health.

This Time in Range report shows a person who spent 75% of their day in target glucose range:

 

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The FreeStyle Libre 2 system help increase %TIR

An independent study published in the New England Journal of Medicine shows that FreeStyle Libre 2 users increased their Time in Range by over 2 hours per day7:

  • 156 people with T1D ≥16 years with HbA1c ≥7.5% participated in a randomised, controlled study7

  • FreeStyle Libre 2 users spent 2.2 hours more time in range per day at 6 months of use vs those using self-monitored blood glucose7

Increased time in range graph

Time in Range & LibreView

Easily visualise Time in Range for your patients with LibreView

LibreView is a secure,8 cloud-based diabetes management system. It provides both healthcare professionals and patients with access to a clear, easy-to-understand reports from compatible FreeStyle glucose monitoring devices. LibreView allows you to create and share standardised, easy-to-read reports from multiple glucose devices into one complete view to aid in better diabetes conversations with your patients and other healthcare professionals.

With the AGP report on LibreView you can:

  • See Time in Range guidelines and an overview of patient glucose data
  • Quickly assess your patient’s Time in Range
  • Identify trends and patterns at a glance
  • Identify specific times of deviation with the Daily Glucose Profiles

Additional Resources

Educational Modules

Learn more about Time in Range and the FreeStyle Libre Portfolio through our Healthcare Professional education modules.

Webinars

We offer various on-demand webinars for Healthcare Professionals.

 

 

 

CME Modules

Take part in our three-part CME accredited webcast programme exploring the growing role of Time In Range as a critical metric of glycaemic control in diabetes management.

 

 

Training Resources

Explore our training resources to help you to help your patients understand Time in Range better.


References & Disclaimers

Images are for illustrative purposes only. Not real patient's data.

1. Battelino, T. Diabetes Care (2019): https://doi.org/10.2337/dci19-0028.

2. Vigersky, RA. Diabetes Technol Ter (2019): https://doi.org/10.1089/dia.2018.0310   

3. Beck, RW. Diabetes Care (2019): https://doi.org/10.2337/dc18-1444.

4. Lu J, et al. Diabetes Technol Ther. 2020 Feb;22:72-78. 

5. Lu J et al. Diabetes Care 2018;41:2370–2376.

6. Li F, et al. Diabetes Res Clin Pract. 2020 Aug;166:108289. doi: 10.1016/j.diabres.2020.108289

7. Leelarathna, L. N Engl J Med. (2022): DOI: 10.1056/NEJMoa2205650.

8. LibreView is ISO27001/27018/27701 certified and HITRUST CSF Certified

^ The international consensus report has been endorsed by the ADA, AACE, AADE, EASD, FEND, ISPAD, JDRF, and PES.

₼ The LibreView data management software is intended for use by both patients and healthcare professionals to assist people with diabetes and their healthcare professionals in the review, analysis, and evaluation of historical glucose meter data to support effective diabetes management. The LibreView software is not intended to provide treatment decisions or to be used as a substitute for professional healthcare advice.

~ Includes percentage of values >13.9 mmol/l.

△ Includes percentage of values <3.0 mmol/l.

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