Clinical Evidence

Clinical benefits for a broad range of T1D and T2D patients

Clinical Evidence
Clinical Evidence
Clinical Evidence

Increased Monitoring Frequency

More frequent glucose monitoring with the FreeStyle Libre system is associated with better diabetes management.1,3,4

increased monitorung frequency increased monitorung frequency

Reduced HbA1c

Use of the FreeStyle Libre system is clinically proven to significantly reduce HbA1c in patients with T2D5,7

A1C 0.9 A1C 0.9
Overall, 0.9% HbA1c reduction in patients with T2D on basal bolus insulin5


target TIR target TIR
43% increase in time in target range

(3.9–10.0 mmol/L) from 11.7 to 16.8 hours a day with increased scan rate2

hyper 63 hyper 63
63% reduction in time spent in hyperglycaemia

across patients with T1D and T2D2

hypo 43 hypo 43
43% reduction in time spent in hypoglycaemia

in patients with T2D4

Making Better Choices

The FreeStyle Libre system helps patients with T2D make better choices

Real World data showed that 95% of patients with T1D and T2D using the FreeStyle Libre system:

✓ Have a better understanding of their glucose fluctuations8

✓ Data from FreeStyle Libre users with T2D showed that users feel more engaged with managing their diabetes4,5


Lifestyle modifications can help lower HbA1c

Patients with T2D who make lifestyle changes, such as diet and physical activity, see improved glucose control.9

making better choices making better choices making better choices

Improve Glycaemic Control in ChildrenѰ

Children and teenagers can successfully improve their glycaemic control with the FreeStyle Libre system

clinical evidence children clinical evidence children
1 hr daily 1 hr daily

Increased time in range by 1 hour/day10 (3.9–10.0 mmol/L)

a1c 0.4 a1c 0.4

Reduced HbA1c by 0.4%10

increased monitorung frequency increased monitorung frequency

Increased the frequency of glucose monitoring to an average of 13x /day vs. SMBG10

reduce hypergycaemia reduce hypergycaemia

Reduced time spent in hyperglycaemia

(>10 mmol/L) by 1 hr/day with no significant increase in time spent in hypoglycaemia (<3.9 mmol/L)10

90 percent of children 90 percent of children

90% of children and teenagers agreed that the FreeStyle Libre system did not get in the way of daily activities10

Additional Resources

Real-World Data

Analysing the impact of the FreeStyle Libre system on the lives of real users.

Educational Modules

Learn more about Time in Range and the FreeStyle Libre system through our Healthcare Professional education modules.


We offer various on-demand webinars for Healthcare Professionals including a spotlight on hypoglycaemia.


Webcast Series

Learn more about Time in Range in our CME accredited three-module webcast series.


Training Resources

Explore our training resources to help you to help your patients understand Time in Range better.

References & Disclaimers

Images are for illustrative purposes only. Not real patient or data.

1. Dunn, T., et al. Real-world flash glucose monitoring patterns and associations between self-monitoring frequency and glycaemic measures: A European analysis of over 60 million glucose tests. Diabetes Research and Clinical Practice; 137(2018) 37-46

2. Lang J, et al. Expanded real-world use confirms strong association between frequency of flash glucose monitoring and glucose control [Poster 972]. Diabetes 2019 Jun; 68(Supplement 1). 972-P.

3. Bolinder, Jan, et al. "Novel Glucose-sensing Technology and Hypoglycaemia in Type 1 Diabetes: a Multicentre, Non-masked, Randomised Controlled Trial." The Lancet 388, no. 10057 (2016): 2254-2263.

4. Haak, Thomas, et al. "Flash Glucose-Sensing Technology as a Replacement for Blood Glucose Monitoring for the Management of Insulin-treated Type 2 Diabetes: a Multicentre, Open-label Randomised Controlled Trial." Diabetes Therapy 8, no. 1 (2017): 55-73.

5. Kröger J, et al. Three European retrospective real-world chart review studies to determine the effectiveness of flash glucose monitoring on HbA1c in adults with type 2 diabetes. Diabetes Ther 2020;11(1):279–91.

6. Evans, Mark, et al. "The Impact of Flash Glucose Monitoring on Glycaemic Control as Measured by HbA1c: a Meta-analysis of Clinical Trials and Real-world Observational Studies." Diabetes Therapy 11, no. 1 (2020): 83-95.

7. Yaron M, et al. Effect of flash glucose monitoring technology on glycemic control and treatment satisfaction in patients with type 2 diabetes. Diabetes Care 2019;42(7):1178–84.

8. Fokkert M, van Dijk P, Edens M, et al. Improved well-being and decreased disease burden after 1-year use of flash glucose monitoring (FLARE-NL4). BMJ Open Diab Res Care. 2019. https://doi:10.1136/bmjdrc-2019-000809.

9. American Diabetes Association Professional Practice Committee. 5. Facilitating behavior change and well-being to improve health outcomes: Standards of Medical Care in Diabetes—2022. Diabetes Care 2022;45 (Suppl. 1):S60–S82

10. Campbell FM, et al. Outcomes of using flash glucose monitoring technology by children and young people with type 1 diabetes in a single arm study.
Pediatr Diabetes 2018;19(7):1294–301. 

Ѱ For children aged 4-12, a caregiver at least 18 years old is responsible for supervising, managing, and assisting them in using the FreeStyle Libre system and interpreting its readings.