There are four key components of an AGP:
- Median
- 25th–75th Percentile
- 5th–95th Percentile
- Target Glucose Range
Each of these elements tells a clear story about your patients’ glucose control and variability over a selected time period.
Ambulatory Glucose Profile
Ambulatory Glucose Profiles (AGPs) reveal glucose trends and patterns at a glance and help identify when patients are out of target range.1
Understanding the AGP components
SOLID GREEN LINE: Median Line
The median line traces the mid-point glucose reading as a measure of average glucose at each point in the modal day and shows whether the average glucose is within the target glucose range and how much it oscillates during the day.2 The goal for the Median Line is for it to be as flat as possible over the entire 24-hour period and within the target glucose range.
INNER GREEN-SHADED BAND:
The 25th to 75th percentile band illustrates when glucose variation is common from one day to the next. The band represents 50% of all glucose readings for the patient at each time point.2 The goal is to reduce the more common day-to-day glucose variability by reducing the width of the 25th to 75th percentile above and below the median line.
OUTER MULTICOLOURED SHADED BAND (LIGHT GREEN / YELLOW / ORANGE / RED):
The visible part of the 5th to 95th percentile includes the readings that reflect less common departures from the daily average glucose. Large excursions above or below the Median Line may indicate poor control for a variety of reasons, but if the 5th to 95th percentile band is wide, it means that occasionally your patient’s glucose control has varied quite a lot from day to day. The goal is to understand whether more extreme glucose readings can be linked to occasional activities that a patient can plan for.
TWO PARALLEL GREEN LINES: Target Range
This is the corridor where glucose levels should be as much as possible. According to international consensus, the target glucose range is usually 3.9 mmol/L–10 mmol/L for adults with type 1 and type 2 diabetes who are not pregnant, not older, or at risk.3
The benefits of reviewing AGP
The benefits of reviewing an AGP during a diabetes clinical review
3-Step guide to interpreting the AGP
AGP & LibreView
Easily visualise AGP for your patients with LibreView₼,5
With the AGP report on LibreView you can:
- See Time in Target guidelines and an overview of patient glucose data
- Quickly assess your patient’s AGP
- Identify trends and patterns at a glance
- Identify specific times of deviation with the Daily Glucose Profiles
References & Disclaimers
Images are for illustrative purposes only. Not real patients, healthcare professionals or data.
1. Wright, E.E. Jr. and Hirsch, |.B.,(2015). The ambulatory glucose profile: a new view of glucose patterns. Journal of Family Practice, 64(12 Suppl),pp.S4-S10.
2. Gibb F. W. et al., AGP in daily clinical practice: a guide for use with the FreeStyle Libre flash glucose monitoring system. British Journal of Diabetes.(2020), https://doi.org/10.15277/bjd.2020.240.
3. Battelino T, Danne T, Bergenstal RM, et al. Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range. Diabetes Care. (2019);42(8):1593-1603.
4. Evans, M., Cranston, I. and Bailey, C. (2017). British Journal of Diabetes, 17(1).
5. LibreView is ISO27001/27018/27701 certified and HITRUST CSF Certified.
₼ The LibreView website is only compatible with certain operating systems and browsers. Please check www.LibreView.com for additional information.
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