Does paracetamol alter the glucose readings of the FreeStyle Libre systems?*
The FreeStyle Libre systems* have no contraindications or warnings for paracetamol use.
In vitro study was conducted to examine the effect of paracetamol, on Libre Sensor glucose readings.^ However, the effect of this substance in vivo has not been studied and may differ.
The finding is as follow: Paracetamol was tested at a concentration of 20 mg/dL (or 1.1mmol/L) in glucose-containing solution (10 times the maximum of the therapeutic range for paracetamol) and demonstrated minimal impact on reported Sensor glucose values.1
* FreeStyle Libre systems refers to the FreeStyle Libre 2 and FreeStyle Libre 3 systems
^ The data from this study was collected using the FreeStyle Libre system. The FreeStyle Libre 2 system has the same features as the FreeStyle Libre system with the exception of optional alarms therefore the study data is applicable to both products.
1. Acetaminophen Interference on ISF Based Glucose Monitoring Systems Alva, S., Chen, T., Naegeli, A. poster presented at DTT 2017