Time in Range

An important metric that goes beyond HbA1c

Time in Range is a metric that complements HbA1c and provides actionable information for you and your patients. It helps you quickly assess patients’ glucose, contextualise their HbA1c and increase their Time in Range.

What is Time in Range?

Time in Range is the percentage of time per day a person spends within target glucose range. The FreeStyle Libre systems automatically calculate the percentage of time your patient spends in, above, or below target range.

The International Consensus sets clear targets for Time in Range1.

Recommended Time in Range for most T1D, T2D, non-pregnant, not older, or at risk adults regardless of insulin therapy

Why is Time in Range Important?

  • Every 10% increase in Time in Range can lower HbA1c by 0.8% in type 1 and type 2 patients2

  • Every 5% (~1 hour per day) increase in Time In Range has positive impact on your patients’ glucose control1

  • Spending more Time in Range can reduce long-term eye and kidney health complications3

  • Easily visualise Time in Range and set clear targets for your patients with the FreeStyle Libre Portfolio

Improved %TIR is associated with reduced risk of long term complications of diabetes

Increased %TIR is correlated with reduced risk of diabetes related heart4, kidney3 and eye3 disease, as well as better peripheral nerve function6

HbA1c has limitations

HbA1c reflects average glucose over the last 2–3 months; it does not show glycaemic excursions of hyper- and hypoglycaemia.1

An increase in Time in Range results in a decrease in HbA1c.

Estimate of HbA1c for a given Time in Range level based on T1D and T2D studies2:

Time in Range & FreeStyle Libre Systems

When your patient scans their sensor, the FreeStyle LibreLink Reader or the FreeStyle Libre reader will automatically calculate the percentage of time they spend in, above, or below target range. This will help identify where your patient needs more support in managing their overall diabetes health.

This Time in Target report shows a person who spent 75% of their day in target glucose range:

The FreeStyle Libre systems can help increase %TIR

Real world data show FreeStyle Libre users increased Time in Range with more frequent scan rate.5

  • Real world data comparing two groups from lowest to highest scan rate (3.5 and 38.5 scans/day)
  • 592,328 patients using the FreeStyle Libre system who scanned more often saw an increase in %TIR

Additional Resources

Webinars

We offer various on-demand webinars for Healthcare Professionals including Understanding Time in Range.

 

 

References & Disclaimers

Images are for illustrative purposes only. Not real patient or data.

1. Battelino T, Danne T, Bergenstal RM, et al. Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range. Diabetes Care. (2019);42(8):1593-1603  

2. Vigersky RA, McMahon C. The relationship of hemoglobin A1c to time-in-range in patients with diabetes. Diabetes Technol Ther. (2019);21(2):81-85    

3. Beck RW et al. Diabetes Care 2019;42:400–405.

4.. Lu J, et al. Diabetes Technol Ther. 2020 Feb;22:72-78.

5. Lang J, Jangam S, Dunn T, Hayter G. Expanded real-world use confirms strong association between frequency of flash glucose monitoring and glucose control [Poster 972]. Diabetes 2019 Jun; 68(Supplement 1)

6. Li F, et al. Diabetes Res Clin Pract. 2020 Aug;166:108289. doi: 10.1016/j.diabres.2020.108289

₼ The LibreView website is only compatible with certain operating systems and browsers. Please check www.LibreView.com for additional information.

◊ .Patients choose which device they want to receive alarms: FreeStyle Libre reader or FreeStyle LibreLink app. They must start their FreeStyle Libre sensor with that selected device. Once the patient scans their FreeStyle Libre sensor with that device, they can receive alarms only on that device. The FreeStyle LibreLink app is only compatible with certain mobile devices and operating systems. Please check the website for more information about device compatibility before using the app. Use of FreeStyle LibreLink requires registration with LibreView. 

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